Which infectious agent causes diseases that are the most difficult to cure?

bacteria
virus
fungus
prion
All known prion diseases affect the structure of the brain or other neural tissue and all are currently untreatable and universally fatal. This includes bovine spongiform encephalopathy (BSE, also known as "mad cow disease") in cattle and Creutzfeldt–Jakob disease (CJD) in humans.
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Answers by country

bacteria
virus
fungus
prion
answers
flagItaly
3%
15%
0%
80%
26
flagPakistan
5%
22%
6%
64%
117
flagGermany
6%
27%
3%
60%
176
flagMalaysia
0%
34%
5%
60%
35
flagGreece
8%
28%
4%
60%
25
flagPoland
8%
28%
7%
54%
21202
flagGhana
4%
40%
0%
54%
22
flagRepublic of Ireland
11%
32%
2%
50%
34
flagthe Netherlands
4%
27%
13%
50%
22
flagIndia
4%
38%
6%
49%
727
flagthe United States
7%
38%
6%
46%
924
flagAustralia
14%
30%
6%
46%
62
flagCanada
6%
44%
4%
45%
75
flagSwitzerland
2%
43%
9%
45%
44
flagthe United Kingdom
5%
41%
7%
44%
270
flagNigeria
4%
52%
0%
42%
21
flagAustria
13%
41%
2%
41%
36
flagthe United Arab Emirates
11%
25%
14%
40%
27
flagIndonesia
15%
35%
10%
40%
20
flagthe Philippines
14%
45%
5%
33%
102