Which infectious agent causes diseases that are the most difficult to cure?

bacteria
virus
fungus
prion
All known prion diseases affect the structure of the brain or other neural tissue and all are currently untreatable and universally fatal. This includes bovine spongiform encephalopathy (BSE, also known as "mad cow disease") in cattle and Creutzfeldt–Jakob disease (CJD) in humans.
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Answers by country

bacteria
virus
fungus
prion
answers
flagItaly
3%
20%
0%
76%
30
flagPakistan
5%
23%
6%
63%
126
flagMalaysia
0%
30%
7%
61%
42
flagGreece
5%
32%
2%
58%
34
flagGermany
7%
31%
4%
55%
283
flagPoland
8%
28%
7%
54%
22305
flagAustralia
12%
28%
5%
52%
78
flagGhana
4%
45%
0%
50%
24
flagIndia
4%
39%
6%
47%
805
flagthe Netherlands
6%
31%
12%
46%
32
flagthe United States
7%
38%
6%
45%
976
flagthe United Kingdom
5%
41%
6%
45%
328
flagCanada
6%
43%
4%
45%
81
flagRepublic of Ireland
15%
35%
2%
45%
40
flagSwitzerland
3%
44%
7%
44%
52
flagIndonesia
15%
35%
10%
40%
20
flagAustria
14%
45%
3%
36%
55
flagNigeria
2%
60%
0%
36%
38
flagthe United Arab Emirates
13%
30%
13%
36%
30
flagthe Philippines
14%
45%
5%
33%
105